王乐明

           “骏马计划”研究员

           办公室:南校区化学楼439

          邮箱:wanglm@imu.edu.cn


 

 

 

教育背景

 

2007-2011郑州大学,理学学士

2011-2016:北京大学,理学博士,导师:黄湧教授

 

工作经历

 

2016-2018:北京大学(深圳研究生院),博士后,合作导师:黄湧教授

2019-2021:珠海中科先进技术研究院,博士后,合作导师:张嘉恒教授

2019-2020:新加坡国立大学,访问学者,合作导师:卢一新教授

2021-2022:深圳萱嘉生物科技有限公司,研发工程师

2022-至今:太阳成集团tyc4633,“骏马计划”研究员

 

 

研究领域

 

1.      有机小分子不对称催化;

2.      活性药物小分子后期修饰;

 

 

发表论文

 

1. Hongbo Qi, Dongmei Chi, Jing He, Leming Wang,* and Shufeng Chen*. Pd-Catalyzed Cascade Intramolecular Heck Cyclization/Dearomatization of Indoles for the Construction of Two All-Carbon Quaternary Centers, Org. Lett. 2022, 24, 8880.

2. Leming Wang, Xinhang Jiang, Jiean Chen* and Yong Huang*. Enantio- and Diastereoselective Hydrofluorination of Enals via N-Heterocyclic Carbene Catalysis, Angew. Chem. Int. Ed. 2019, 58, 7410.  

3. Leming Wang, Qian Wang, Jiean Chen* and Yong Huang*. Switching Reaction Pathways by Cooperative Catalysis of N-Heterocyclic Carbene and Lewis Acids, Acta Chim. Sinica 2018, 76, 850.

4. Jiean Chen, Pengfei Yuan, Leming Wang, and Yong Huang*. Enantioselective β‑Protonation of Enals via a Shuttling Strategy, J. Am. Chem. Soc. 2017, 139, 7045.

5. Leming Wang, Jiean Chen and Yong Huang*. Highly Enantioselective Aza-Michael Reaction between Alkyl Amines and β-Trifluoromethyl β-Aryl Nitroolefins, Angew. Chem. Int. Ed. 2015, 54, 15414.

6. Jiean Chen, Sixuan Meng, Leming Wang, Hongmei Tang and Yong Huang*. Highly enantioselective sulfa-Michael addition reactions using N-heterocyclic carbene as a noncovalent organocatalyst, Chem.Sci. 2015, 6, 4184.

7. Junlin Zhang, Leming Wang, Qi Liu, Zhen Yang* and Yong Huang*. Synthesis of α,β-unsaturated carbonyl compounds via a visible light promoted organocatalytic aerobic oxidation, Chem. Commun. 2013, 49, 11662.